Skin and Airway Exposure to Allergens Promotes Development of Peanut allergy by Distinct Mechanisms in Mice.

The mechanisms of peanut allergy are not fully understood. T follicular helper (Tfh) cells that produce IL-13 (i.e., Tfh13 cells) are implicated in production of IgE antibody associated with anaphylaxis. The goal of this project was to elucidate the immunologic mechanisms involved in developing peanut allergy by using mouse models.

Source: Journal of Allergy and Clinical Immunology - February 1, 2024 Category: Allergy & Immunology Authors: Mayumi Matsunaga, Jyoti Lama, Ryusuke Hayashi, Yuya Yoshida, Takao Kobayashi, Koji Iijima, Hirohito Kita Source Type: research