Wildfire Smoke Exposure during SARS-CoV-2 Vaccination Impairs Immunity via Natural Killer Cell derived IL-13

Wildfires are increasing in intensity, duration, and frequency with smoke plums affecting the lives of millions over large geographic areas. The immune modulatory effects of wildfire smoke are unclear. We previously showed that a major wildfire smoke component, ozone, inhibited dendritic cell lymph node homing (an essential process in vaccine immunity) by suppressing NK cell-derived IFN- γ expression in mice.

Source: Journal of Allergy and Clinical Immunology - February 1, 2024 Category: Allergy & Immunology Authors: Gursharan Kaur Sanghar, Melissa Teuber, Resmi Ravindran, Emma Keller, Pedro Hernandez, Sophie Krauss, Angela Linderholm, Gabrielle Echt, Kaelyn Tuermer-Lee, Maya Juarez, Timothy Albertson, Imran Khan, Angela Haczku Source Type: research