Computational validation of clonal and subclonal copy number alterations from bulk tumor sequencing using CNAqc
Copy number alterations (CNAs) are among the most important genetic events in cancer, but their detection from sequencing data is challenging because of unknown sample purity, tumor ploidy, and general intra-t...
Source: Genome Biology - Category: Genetics & Stem Cells Authors: Alice Antonello, Riccardo Bergamin, Nicola Calonaci, Jacob Househam, Salvatore Milite, Marc J. Williams, Fabio Anselmi, Alberto d ’Onofrio, Vasavi Sundaram, Alona Sosinsky, William C. H. Cross and Giulio Caravagna Tags: Method Source Type: research