Efficacy of Vagus Nerve Stimulation in Managing Drug-Resistant Absence Epilepsy Syndromes

Absence epilepsy is the most common form of pediatric epilepsy, manifesting during both childhood and adolescence. Childhood absence epilepsy (CAE) is far more common than juvenile (JAE) and is also more likely to resolve by adulthood[1,2]. Ethosuximide is first line for management for both[3]. However if a patient doesn't adequately respond to the first line therapy, the best next step in management is typically valproic acid[4] in males or non-reproductive age females or lamotrigine[5], either as a mono therapy or used in combination with one another[5].
Source: Seizure: European Journal of Epilepsy - Category: Neurology Authors: Source Type: research