Nontuberculous mycobacterial pulmonary infections in the era of elexacaftor-tezacaftor-ivacaftor

Nontuberculous mycobacteria (NTM) are environmental pathogens that can cause airway infection in susceptible hosts, including people with cystic fibrosis (pwCF). NTM infection in pwCF has been associated with adverse outcomes including poorer lung function and increased rate of lung function decline [1,2]. NTM infection in pwCF is also highly variable and can range from a transient single positive culture to persistent indolent infection to persistent infection with clinical decline attributed to NTM infection (i.e., NTM pulmonary disease (NTM-PD)) [2].
Source: Journal of Cystic Fibrosis - Category: Respiratory Medicine Authors: Source Type: research