Hepatoprotective Phenylpropanoid Glycosides from Highland Barley Monascus purpureus

A new phenylpropanoid glycoside, named 4-O-β-D-glucopyranosyl-7-phenyl-9-propenyl ketone-9-O-β-Dglucopyranosyl-(6 ′′→1′′′)-6′′-O-α-L-rhamnopyranose (1), and four known phenylpropanoid glycosides2 –5 were isolated from highland barleyMonascus purpureus Went for the first time. Their structures were determined by their comprehensive spectral data and reported references. Compounds1 –5 were evaluated for their hepatoprotective activities against D-galactosamine-induced toxicity in WB-F344 cells with bicyclol as positive control. As a result, compounds1 and2 exhibited moderate hepatoprotective activities.

Source: Chemistry of Natural Compounds - January 30, 2024 Category: Chemistry Source Type: research