NMNAT2 supports vesicular glycolysis via NAD homeostasis to fuel fast axonal transport

Bioenergetic maladaptations and axonopathy are often found in the early stages of neurodegeneration. Nicotinamide adenine dinucleotide (NAD), an essential cofactor for energy metabolism, is mainly synthesized ...

Source: Molecular Neurodegeneration - January 29, 2024 Category: Neurology Authors: Sen Yang, Zhen-Xian Niou, Andrea Enriquez, Jacob LaMar, Jui-Yen Huang, Karen Ling, Paymaan Jafar-Nejad, Jonathan Gilley, Michael P. Coleman, Jason M. Tennessen, Vidhya Rangaraju and Hui-Chen Lu Tags: Research article Source Type: research