Activated protein C and free protein S in patients with mild to moderate bleeding disorders

Underlying mechanisms for bleeding and impaired thrombin generation (TG) and plasma clot formation (PCF) in patients with mild to moderate bleeding disorders (MBDs) are still to be elucidated, especially in bleeding disorder of unknown cause (BDUC). The role of the natural anticoagulants activated protein C (APC) and free protein S (PS) has not yet been investigated in this patient population.

Source: Thrombosis Research - January 25, 2024 Category: Hematology Authors: Dino Mehic, Theresa Schramm, Birgit Forstner-Bergauer, Helmuth Haslacher, Cihan Ay, Ingrid Pabinger, Johanna Gebhart Tags: Full Length Article Source Type: research