Identification of squalene epoxidase in triterpenes biosynthesis in Poria cocos by molecular docking and CRISPR-Cas9 gene editing

Squalene epoxidase is one of the rate-limiting enzymes in the biosynthetic pathway of membrane sterols and triterpenoids. The enzyme catalyzes the formation of oxidized squalene, which is a common precursor of...

Source: Microbial Cell Factories - January 25, 2024 Category: Microbiology Authors: Xiao-liu Liu, Jing Xie, Zhen-ni Xie, Can Zhong, Hao Liu, Shui-han Zhang and Jian Jin Tags: Research Source Type: research