Effects of mandibular advancement devices on the evolution of obstructive sleep apnea

ConclusionsMADs led to a significant improvement in  AHI and other polygraphic parameters from the onset of use. The decrease of clinical symptoms (drowsiness and fatigue) was more complex to interpret because of the small decreases observed. The absence of concordance between AHI improvement and clinical symptoms was nevertheless objectively quan tified and symptoms were alleviated with advancements. The findings suggest that it may be appropriate to use clinical symptoms as a main aim of titration, since the improvement in AHI is reached at the onset of MAD use.
Source: Sleep and Breathing - Category: Respiratory Medicine Source Type: research