Association of indicators of extensive disease and rifampin-resistant tuberculosis treatment outcomes: an individual participant data meta-analysis

Conclusion
Only the combination of AFB smear-positivity and lung cavitation was associated with unfavourable outcomes, suggesting they may benefit from stronger regimens.

Source: Thorax - January 18, 2024 Category: Respiratory Medicine Authors: Campbell, J. R., Brode, S. K., Barry, P., Bastos, M. L., Bonnet, M., Guglielmetti, L., Kempker, R., Klimuk, D., Laborin, R. L., Milanov, V., Singla, R., Skrahina, A., Trajman, A., van der Werf, T. S., Viiklepp, P., Menzies, D. Tags: Editor's choice, Thorax Tuberculosis Source Type: research