Interactions of obesity, body shape, diabetes and sex steroids with respect to prostate cancer risk in the UK Biobank cohort

ConclusionsObesity and diabetes showed synergistic inverse associations with prostate cancer risk, likely involving testosterone reduction for diabetes and oestrogen generation for obesity, which were attenuated for high-ABSI. HI and SHBG showed synergistic inverse associations with prostate cancer risk.

Source: Cancer Medicine - January 18, 2024 Category: Cancer & Oncology Authors: Sofia Christakoudi, Konstantinos K. Tsilidis, Evangelos Evangelou, Elio Riboli Tags: RESEARCH ARTICLE Source Type: research