Role of Perampanel in the Management of Pediatric Epilepsies in Asia: Expert Opinion

Management of pediatric epilepsies poses unique challenges around diagnosis, treatment options, comorbidities, and the potential for these factors to interact with processes in the developing brain. In pediatric patients, broad-spectrum antiseizure medications (ASMs) with minimal potential for adverse events (AEs) and limited impact on cognition and behavior are preferred. Perampanel is a first-in-class ASM with broad-spectrum efficacy, a tolerable safety profile, minimal negative impact on cognitive function, and other features that make it a viable treatment option in this patient population.

Source: Pediatric Neurology - October 3, 2023 Category: Neurology Authors: Wang-Tso Lee, Derrick Wei Shih Chan, Sheffali Gulati, Surachai Likasitwattanakul, Byung Chan Lim, Akihisa Okumura, Benilda Sanchez-Gan, Yi Wang, Kam Tim Liu Tags: Review Article Source Type: research