Structural Predictors of Lung Function Decline in Young Smokers with Normal Spirometry

CONCLUSIONS: Radiologic abnormalities on CT are already established in young smokers with normal lung function and is associated with FEV1 loss independently of the impact of symptoms. Structural abnormalities are present early in the natural history of COPD and are markers of disease progression. This article is open access and distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives License 4.0 (http://creativecommons.org/licenses/by-nc-nd/4.0/).PMID:38175920 | DOI:10.1164/rccm.202307-1203OC

Source: Am J Respir Crit Car... - January 4, 2024 Category: Intensive Care Authors: Andrew I Ritchie Gavin C Donaldson Eric A Hoffman James P Allinson Chloe I Bloom Charlotte E Bolton Gourab Choudhury Sarah E Gerard Junfeng Guo Luana Alves-Moreira Lorcan McGarvey Elizabeth Sapey Robert A Stockley K P Yip Dave Singh Tom Wilkinson Malin Fa Source Type: research