The synergism of cytosolic acidosis and reduced NAD+/NADH ratio is responsible for lactic acidosis-induced vascular smooth muscle cell impairment in sepsis
During sepsis, serve vascular dysfunctions lead to life-threatening multiple organ failure, due to vascular smooth muscle cells (VSMC) impairments, resulting in vasoplegia, hypotension and hypoperfusion. In ad...
Source: Journal of Biomedical Science - Category: Biomedical Science Authors: Philipp Terpe, Stefanie Ruhs, Virginie Dubourg, Michael Bucher and Michael Gekle Tags: Research Source Type: research
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