Puerarin protects renal ischemia-reperfusion injury in rats through NLRP3/Caspase-1/GSDMD pathway

CONCLUSIONS: Puerarin can inhibit the activation of NLRP3/Caspase-1/GSDMD pathway, inhibit inflammatory response and pyroptosis, and enhance the antioxidant capacity of kidney, thereby protecting renal I/R injury in rats.PMID:38055404 | PMC:PMC10691188 | DOI:10.1590/acb387323

Source: Acta Cirurgica Brasileira - December 6, 2023 Category: Surgery Authors: Kangyu Wang Zhao Tang Shuai Liu Yan Liu Huiqing Zhang Haocheng Zhan Source Type: research