Mitonuclear epistasis involving TP63 and haplogroup Uk: risk of rapid progression of knee OA in patients from the OAI

To investigate genetic interactions between mtDNA haplogroups and nuclear single nucleotide polymorphisms (nSNPs) to analyze their impact on the development of the rapid progression of knee osteoarthritis (OA).

Source: Osteoarthritis and Cartilage - January 6, 2024 Category: Rheumatology Authors: Alejandro Dur án-Sotuela, Natividad Oreiro, Mercedes Fernández-Moreno, Jorge Vázquez-García, Sara Relaño-Fernández, Vanesa Balboa-Barreiro, Francisco J. Blanco, Ignacio Rego-Pérez Source Type: research