Precancerous nature of intestinal metaplasia with increased chance of conversion and accelerated DNA methylation

Conclusions
IM cells were considered to have a precancerous nature potentially with an increased chance of converting into cancer cells, and an accelerated DNA methylation induction due to abnormal NOS2 expression.

Source: Gut - January 5, 2024 Category: Gastroenterology Authors: Takeuchi, C., Yamashita, S., Liu, Y.-Y., Takeshima, H., Sasaki, A., Fukuda, M., Hashimoto, T., Naka, T., Ishizu, K., Sekine, S., Yoshikawa, T., Hamada, A., Yamamichi, N., Fujishiro, M., Ushijima, T. Tags: Gut Gastroduodenal Source Type: research