Intra-abdominal Inflammatory Myofibroblastic Tumour (IMFT) —Uncommon Entity

We report a case of multifocal IMFT affecting the GI tract which was managed with gross total excision followed by chemotherapy. Surgical resection remains the treatment of choice. The role of chemotherapy and radiation therapy remains limited. The aetiology of these tumours remains unclear and is mostly ALK-positive that could be targeted. Local recurrences are common and hence require close follow-up. The risk of recurrences and metastasis is increased in cases with TP53 positivity, aneuploidy and recurrent lesions.
Source: Indian Journal of Surgical Oncology - Category: Cancer & Oncology Source Type: research