Programmed death of macrophages in atherosclerosis: mechanisms and therapeutic targets

Nature Reviews Cardiology, Published online: 02 January 2024; doi:10.1038/s41569-023-00957-0Macrophages in atherosclerotic plaques can undergo apoptosis and several forms of regulated necrosis, including necroptosis, pyroptosis and ferroptosis. In this Review, De Meyer and colleagues describe the various forms of programmed macrophage death in atherosclerosis and the potential therapeutic implications.

Source: Nature Reviews Cardiology - January 2, 2024 Category: Cardiology Authors: Guido R. Y. De Meyer Michelle Zurek Pauline Puylaert Wim Martinet Source Type: research