Non-Adherence to COPD Medications and its Association with Adverse Events: A Longitudinal Population Based Cohort Study of Older Adults

CONCLUSION: After accounting for time varying confounding by COPD severity, the highest time varying 90-days adherence was associated with an increased risk of both COPD related ED visits and hospitalizations compared to the lowest adherence categories. Differences in COPD severity between adherence categories, perception of need for medication management in the higher adherence categories, and potential residual confounding makes it difficult to disentangle the independent effects of adherence from the severity of the condition itself.PMID:38141744 | DOI:10.1016/j.annepidem.2023.12.003

Source: Annals of Epidemiology - December 23, 2023 Category: Epidemiology Authors: Daniala L Weir Yu Qing Bai Kednapa Thavorn Sara Guilcher Salmaan Kanji Sunita Mulpuru Walter Wodchis Source Type: research