Total and segmental phase angle in a cohort of hospitalised patients with covid-19: mortality prediction and changes throughout hospitalisation

This study aimed to identify the total PhA cut-off point associated with mortality risk and changes in body composition within a week of hospitalisation in non-critical hospitalised patients with COVID-19. A cohort study was conducted in which patients underwent a complete nutritional assessment upon admission and after seven days, if possible, and they were followed up until hospital discharge or death. A receiver operating characteristic curve was constructed to determine the PhA cut-off point, and the Kaplan-Meier estimator was used to determine survival analysis. Segmental and complete body compositions on admission and after 7 days were compared. We included 110 patients (60 men) with a mean age of 50.5 ± 15.0 years and a median body mass index of 28.5 (IQR, 25.6 to 33.5) kg/m2. The median length of hospital stay was 6 (IQR, 4 to 9) days, and the mortality rate was 13.6%. The PhA cut-off point obtained was 4°, with significant differences in the survival rate (p<0.001) and mortality (HR=5.81, 95% CI: 1.80 to 18.67, p= 0.003). Segmental and whole-body compositions were negatively affected within one week of hospitalisation, with changes in the approach by the graphical method in both sexes. Nutritional status deteriorates within a week of hospitalisation. PhA <4° is strongly associated with increased mortality in non-critical hospitalised patients with COVID-19.PMID:38149452 | DOI:10.1017/S0007114523002994
Source: The British Journal of Nutrition - Category: Nutrition Authors: Source Type: research