Estrogen as a guardian of auditory health: Tsp1-CD47 axis regulation and noise-induced hearing loss

CONCLUSIONS: OVX rats were more susceptible to NIHL, and the protective effect of estrogen was achieved through regulation of the Tsp1-CD47 axis. This study presents a novel mechanism through which estrogen regulates NIHL and offers a potential intervention strategy for the clinical treatment of NIHL.PMID:38108225 | DOI:10.1080/13697137.2023.2287632

Source: Climacteric - December 18, 2023 Category: Geriatrics Authors: X Wang H Zheng B Yang M Zu Z Wang J Zhang F Zheng M Yang M C F Tong L Zhao W Bai Source Type: research