Aggregates of non-muscular myosin IIA in erythrocytes associate with GATA1- and GFI1B-related thrombocytopenia

CONCLUSIONS: Aggregates of NMMIIA in the erythrocytes associate with GATA1-RT and GFI1B-RT and can facilitate their diagnosis on the blood smears. This hitherto unreported finding might represent a novel marker of dyserythropoiesis assessable in peripheral blood.PMID:38103735 | DOI:10.1016/j.jtha.2023.12.007

Source: Hamostaseologie - December 16, 2023 Category: Hematology Authors: Carlo Zaninetti Jose' Rivera Leonard Vater Sandra Ohlenforst Eva Lein øe Doris B öckelmann Kathleen Freson Thomas Thiele Houssain Makhloufi Matthias Rath Wolfgang Eberl Martina Wolff Carmen Freyer Jan Wesche Barbara Zieger Ute Felbor Florian H Heidel An Source Type: research