Biologics for inherited disorders of keratinisation: A  systematic review

CONCLUSIONS: Whilst biologics may be considered in cases of inherited keratinisation disorders recalcitrant to standard therapy, definitive conclusions are prohibited by the low-level of evidence and substantial heterogeneity in methodology across the included studies. Establishment of consensus definitions, and randomised clinical trials may help ascertain the efficacy and safety of biologic therapy in this context and establish the best agent and dosing protocol for each disorder.PMID:38126177 | DOI:10.1111/ajd.14197
Source: The Australasian Journal of Dermatology - Category: Dermatology Authors: Source Type: research