Cover Image

Site-specific photo-crosslinking/cleavage, using genetic code expansion technologies, enables identification of protein-protein interface. The method reveals that at least two interfaces are involved in the homophilic interaction of lysosomal-associated membrane protein type 2A (LAMP2A) in mammalian cells (upper panels), which requires a trimeric or higher oligomeric assembly of adjacent LAMP2A molecules (lower panels). For details, see: Terasawa and Seike et al., Protein Science, 2023.https://doi.org/10.1002/pro.4823
Source: Protein Science - Category: Biochemistry Tags: Cover Image Source Type: research