Vivax malaria and Duffy antigen: Stop being so negative

Cell Host Microbe. 2023 Dec 13;31(12):1959-1960. doi: 10.1016/j.chom.2023.11.017.ABSTRACTDuffy blood group antigen (Duffy antigen/receptor for chemokines, atypical chemokine receptor-1, Duffy antigen), an essential Plasmodium vivax invasion receptor, is absent in most Africans. In this issue, two papers show erythroid precursors from Duffy-negative individuals transiently surface-express Duffy antigen and support vivax infection, potentially explaining low-density vivax infections across Africa.PMID:38096790 | DOI:10.1016/j.chom.2023.11.017
Source: Cell Host and Microbe - Category: Microbiology Authors: Source Type: research