Mechanism-aware and multimodal AI: beyond model-agnostic interpretation

Trends Cell Biol. 2023 Dec 11:S0962-8924(23)00235-0. doi: 10.1016/j.tcb.2023.11.002. Online ahead of print.ABSTRACTArtificial intelligence (AI) is widely used for exploiting multimodal biomedical data, with increasingly accurate predictions and model-agnostic interpretations, which are however also agnostic to biological mechanisms. Combining metabolic modelling, 'omics, and imaging data via multimodal AI can generate predictions that can be interpreted mechanistically and transparently, therefore with significantly higher therapeutic potential.PMID:38087709 | DOI:10.1016/j.tcb.2023.11.002

Source: Trends in Cell Biology - December 13, 2023 Category: Cytology Authors: Annalisa Occhipinti Suraj Verma Le Minh Thao Doan Claudio Angione Source Type: research