L-carnitine pretreatment ameliorates heat stress-induced acute kidney injury by restoring mitochondrial function of tubular cells

In conclusion, carnitine insufficiency may be closely associated with severe heat-related illness and related AKI. Enhancement of the FAO pathway by L-carnitine pretreatment may prevent heat stress-induced AKI by restoring mitochondrial function.PMID:38095023 | DOI:10.1152/ajprenal.00196.2023

Source: Am J Physiol Renal P... - December 14, 2023 Category: Urology & Nephrology Authors: Hiroyasu Goto Hiroyuki Nakashima Kazuma Mori Keiko Tanoue Seigo Ito Bradley M Kearney Azusa Kato Masahiro Nakashima Toshihiko Imakiire Hiroo Kumagai Manabu Kinoshita Naoki Oshima Source Type: research