Loop gain response to increased cerebral blood flow at high altitude

CONCLUSION: Pharmacological elevation in CBF significantly reduced LG and severity of CSA. We speculate the effect was on HCVR "controller gain," rather than "plant gain," because PaCO2 and VE were unchanged. An effect via reduced circulation time is unlikely, as the respiratory-cycle length did not change.PMID:38085496 | DOI:10.1007/s11325-023-02956-4

Source: Sleep and Breathing - December 12, 2023 Category: Sleep Medicine Authors: Andrew Burgess Gareth Andrews Katie M E Colby Samuel J E Lucas Kate Sprecher Joseph Donnelly Philip N Ainslie Aparna S Basnet Keith R Burgess Source Type: research