Assessment of serum calprotectin as a marker of  inflammation in cattle with traumatic reticuloperitonitis

Acta Vet Hung. 2023 Dec 11. doi: 10.1556/004.2023.00878. Online ahead of print.ABSTRACTCalprotectin (CP) is an inflammatory marker. The aim of the current study was to investigate oxidative stress and changes in CP in cattle with traumatic reticuloperitonitis (TRP). The study was divided into two groups, experimental (TRP) and healthy control group, with 10 animals in each group. Total leucocyte count, neutrophil and lymphocyte counts were higher in the TRP group compared to the control group and this increase was statistically significant (P < 0.001). The level of malondialdehyde (MDA) in TRP group was statistically significantly higher than the control group (P < 0.001). The level of glutathione (GSH) in the TRP group was statistically significantly lower than in the control group (P < 0.001). Serum Amyloid A (SAA) and CP values were higher in the TRP group and this difference was statistically significant (P < 0.001). It was concluded as a result of ROC analysis that CP, which has similar values with SAA, can be used diagnostically to confirm the inflammatory status in cattle with TRP.PMID:38078926 | DOI:10.1556/004.2023.00878
Source: Acta Veterinaria Hungarica - Category: Veterinary Research Authors: Source Type: research