Effect of Roux-en-Y Gastric Bypass on Circulating Oxylipin Profile in Women with Obesity and Type 2 Diabetes

Chronic inflammation associated with obesity directly contributes to the induction and perpetuation of metabolic diseases, including insulin resistance and type 2 diabetes (T2D).[1] Roux-en-Y gastric bypass (RYGB) is one of the most effective therapies for treating obesity-associated T2D.[2] RYGB is associated with improved pro-oxidative leukocyte status and decreased levels of several pro-inflammatory proteins, suggesting that the attenuation of the inflammatory response is one of the pathways involved in the metabolic improvements observed in the post-operative period.
Source: Prostaglandins, Leukotrienes and Essential Fatty Acids - Category: Biomedical Science Authors: Tags: Original research article Source Type: research