Pharmacokinetics/pharmacodynamics analysis and establishment of optimal dosing regimens using unbound cefmetazole concentration for patients infected with Extended ‐Spectrum β‐lactamase producing Enterobacterales (ESBL‐E)

ConclusionsThe nomogram for CMZ regimens established by PK/PD analysis of measured CMZ concentrations enables optimal CMZ dosing for ESBL-E-infected patients.

Source: Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy - December 11, 2023 Category: Drugs & Pharmacology Authors: Takaya Namiki, Yuta Yokoyama, Hideki Hashi, Rentaro Oda, Aya Jibiki, Hitoshi Kawazoe, Kazuaki Matsumoto, Sayo Suzuki, Tomonori Nakamura Tags: RESEARCH ARTICLE Source Type: research