Translating mosquito viromes into vector management strategies

Trends Parasitol. 2023 Dec 7:S1471-4922(23)00282-9. doi: 10.1016/j.pt.2023.11.002. Online ahead of print.ABSTRACTMosquitoes are best known for transmitting human and animal viruses. However, they also harbour mosquito-specific viruses (MSVs) as part of their microbiota. These are a group of viruses whose diversity and prevalence overshadow their medically relevant counterparts. Although metagenomics sequencing has remarkably accelerated the discovery of these viruses, what we know about them is often limited to sequence information, leaving much of their fundamental biology to be explored. Understanding the biology and ecology of MSVs can enlighten our knowledge of virus-virus interactions and lead to new innovations in the management of mosquito-borne viral diseases. We retrace the history of their discovery and discuss research milestones that would line the path from mosquito virome knowledge to vector management strategies.PMID:38065789 | DOI:10.1016/j.pt.2023.11.002

Source: Trends in Parasitology - December 8, 2023 Category: Parasitology Authors: Cassandra Koh Maria-Carla Saleh Source Type: research