METTL14 knockdown inhibits the pyroptosis in the sepsis-induced acute lung injury through regulating the m6A modification of NLRP3

Conclusion: This study demonstrated that METTL14 knockdown inhibited the pyroptosis in the sepsis-induced ALI progression through decreasing the NLRP3 levels dependent on m6A methylation modification.PMID:38047519 | DOI:10.1080/01902148.2023.2288182

Source: Experimental Lung Research - December 4, 2023 Category: Respiratory Medicine Authors: Jianting Gao Huizhen Chen Yong Zhang Sun Yu Yiyi Wu Qiuyan Wang Zhenfei Yu Source Type: research