Resting State fMRI Network Association with Mortality, Epilepsy, Cognition, and Motor Two-Year Outcomes in Suspected Severe Neonatal Acute Brain Injury

In acute brain injury of neonates, resting-state functional MRI (RS) showed that disrupted connectivity was incrementally associated with consciousness, mortality, cognitive and motor development, and epilepsy, with correction for multiple comparisons, at 6 months post-gestation in neonates with suspected acute brain injury (ABI). However, there are relatively few developmental milestones at 6 months to benchmark against, and it is more difficult to determine at this younger age if behaviorally an infant is having seizures to raise suspicion for epilepsy.

Source: Pediatric Neurology - December 9, 2023 Category: Neurology Authors: Varina L. Boerwinkle, Iliana Manj ón, Bethany L. Sussman, Alyssa McGary, Lucia Mirea, Kirsten Gillette, Jordan Broman-Fulks, Emilio G. Cediel, Martin Arhin, Senyene E. Hunter, Sarah N. Wyckoff, Kimberlee Allred, Deborah Tom Tags: Research Paper Source Type: research