Age at Natural Menopause, Reproductive Lifespan and the Risk of Late-onset Psoriasis and Psoriatic Arthritis in Women: A Prospective Cohort Study

While a peak incidence of psoriasis in women around 60 years of age has been observed, the link between reproductive lifespan and late-onset psoriatic diseases is underexplored. The current study aims to elucidate the association between reproductive lifespan and the risk of late-onset psoriasis and psoriatic arthritis (PsA). Utilizing the UK Biobank data, we conducted a prospective cohort study in postmenopausal women without baseline psoriatic diseases. The exposure variables included age at natural menopause (ANM) and duration from menarche to menopause, termed reproductive years (RYs).

Source: Journal of Investigative Dermatology - December 9, 2023 Category: Dermatology Authors: Yi Xiao, Yan Yi, Danrong Jing, Songchun Yang, Yeye Guo, Hui Xiao, Yehong Kuang, Wu Zhu, Jing Zhao, Yanping Li, Hong Liu, Jinchen Li, Xiang Chen, Minxue Shen Tags: Original Article Source Type: research