A First-in-Human Study of Brozopentyl Sodium, following Single and Multiple Ascending Intravenous Infusion in Chinese Healthy Volunteers

CONCLUSION: BZP displayed safety, good tolerability and predictable PK characteristics following both single and multiple ascending intravenous administrations. These findings provide a basis for further clinical development of BZP for ischemic stroke patients.PMID:38056780 | DOI:10.1016/j.ejps.2023.106663

Source: European Journal of Pharmaceutical Sciences - December 6, 2023 Category: Drugs & Pharmacology Authors: Xiao-Yan Sheng Ran Xie Lu-Hua Wei Bo Jia Yun-Feng Li Zhi-Guo Zheng Xia Zhao Yi-Min Cui Source Type: research