Clonal expansion of CD8+ T cells in aged mice linked to pro-atherogenic phenotype

Nature Reviews Cardiology, Published online: 08 December 2023; doi:10.1038/s41569-023-00981-0In aged mice, but not young mice, with atherosclerosis, depletion of CD8+ T cells significantly reduces atherosclerotic lesion size and necrotic core area.

Source: Nature Reviews Cardiology - December 8, 2023 Category: Cardiology Authors: Karina Huynh Source Type: research