Sphingosine-1-phosphate receptor 3 is a non-hormonal target to counteract endometriosis-associated fibrosis

To study the molecular mechanisms responsible for fibrosis in endometriosis by investigating whether the protein expression levels of sphingosine-1-phosphate receptor 3 (S1PR3), one of the five specific receptors of the bioactive sphingolipid sphingosine 1-phosphate (S1P), correlated with fibrosis extent in endometriotic lesions and which are the cellular mechanisms involved in this process.

Source: Fertility and Sterility - December 7, 2023 Category: Reproduction Medicine Authors: Caterina Bernacchioni, Margherita Rossi, Valentina Vannuzzi, Matteo Prisinzano, Isabelle Seidita, Maryam Raeispour, Angela Muccilli, Francesca Castiglione, Paola Bruni, Felice Petraglia, Chiara Donati Tags: Endometriosis Source Type: research