A novel quantitative urine LAM antigen strip for point-of-care tuberculosis diagnosis in non-HIV adults

We read with interest the systematic review by Ashar et al. in which the implementation of lateral flow lipoarabinomannan (LAM)-based tuberculosis (TB) testing among HIV-positive inpatients is recommended.1  Detecting urinary LAM may represent a promising approach to address the gap in TB diagnosis,2 which is rapid, economical, and available at point-of-care (POC) and utilizes non-sputum samples to cater to populations who have difficulty producing diagnostic sputum samples.1,3 However, limited sens itivity has impeded its widespread adoption.

Source: Journal of Infection - November 28, 2023 Category: Infectious Diseases Authors: Zhen Huang, Huan Huang, Jing Hu, Lu Xia, Xuhui Liu, Rong Qu, Xiaolin Huang, Yang Yang, Kang Wu, Ruiqing Ma, Jinchuan Xu, Zhenyan Chen, Yuhao Wu, Juan Yang, Yong Fang, Jianfeng Zeng, Weihua Lai, Guodong Sui, Wei Sha, Yonghua Xiong, Shuihua Lu, Xiao-Yong Fa Tags: Letter to the Editor Source Type: research