Possibility of perilipin5 as a therapeutic target for anti-obesity and anti-metabolic diseases

Rationale: Perilipin 5 (PLIN5) is present on the surface of lipid droplets and is involved in lipid droplet homeostasis by regulating fatty acid storage and release. However, the role of PLIN5 in the interaction mechanism between mitochondria and lipid droplets remains unclear. Therefore, investigating the role of PLIN5 in this process is crucial in understanding lipid metabolism homeostasis and its potential as a therapeutic target for treating obesity and metabolic diseases.
Source: Clinical Nutrition ESPEN - Category: Nutrition Authors: Source Type: research