Stevioside attenuates bleomycin-induced pulmonary fibrosis by activating the Nrf2 pathway and inhibiting the NF- κB and TGF-β1/Smad2/3 pathways

Conclusion: STE may alleviate oxidative stress by activating the Nrf2 pathway, suppress the inflammatory response by downregulating the NF-κB pathway, and inhibit EMT progression by blocking the TGF-β1/Smad2/3 pathway, thereby improving BLM-induced PF.PMID:38044666 | DOI:10.1080/01902148.2023.2286465
Source: Experimental Lung Research - Category: Respiratory Medicine Authors: Source Type: research