Development and validation of equilibrium dialysis UHPLC-MS/MS measurement procedures for total and unbound concentrations of bictegravir, dolutegravir, darunavir and doravirine in human plasma. Application to patients with HIV

CONCLUSIONS: The UHPLC-MS/MS procedures developed could be used for research purposes and therapeutic drug monitoring of antiretrovirals in routine clinical practice.PMID:38042460 | DOI:10.1016/j.cca.2023.117678

Source: International Journal of Clinical Chemistry - December 2, 2023 Category: Chemistry Authors: Ra úl Rigo-Bonnin Laura Garc ía-Tejada Virg ínia Mas-Bosch Arkaitz Imaz Juan Manuel Tiraboschi Sof ía Scévola Jordi Niub ó Antonio Navarro-Alcaraz Daniel Podzamczer Source Type: research