Comprehensive gene profiling of the metabolic landscape of humanized livers in mice
The human liver transcriptome is complex and highly dynamic, e.g., one gene may produce multiple distinct transcripts, each with distinct posttranscriptional modifications. Direct knowledge of the transcriptome dynamics, however, is largely obscured by the inaccessibility of human liver to treatments and the insufficient annotation of the human liver transcriptome at transcript and RNA modifications levels.
Source: Journal of Hepatology - Category: Gastroenterology Authors: Chengfei Jiang, Ping Li, Yonghe Ma, Nao Yoneda, Kenji Kawai, Shotaro Uehara, Yasuyuki Ohnishi, Hiroshi Suemizu, Haiming Cao Tags: Research Article Source Type: research