Predisposing factors for adrenal crisis in chronic adrenal insufficiency: a case-control study

CONCLUSION: Higher glucocorticoid dosages in high-risk patients, despite unaffected cortisol metabolism, may be linked to decreased cortisol sensitivity or impaired glucocorticoid absorption. Proactive dose adjustments show a protective effect against AC, regardless of biological vulnerability.PMID:38006230 | DOI:10.1093/ejendo/lvad149

Source: European Journal of Endocrinology - November 25, 2023 Category: Endocrinology Authors: Irina Chifu Stephanie Burger-Stritt Anna Schrader Sabine Herterich Janik Freytag Max Kurlbaum Nora Vogg Johanna Werner Marcus Quinkler Stefanie Hahner Source Type: research