Cerebral proliferative angiopathy: Rare case of seizures, bone erosion, and pulsatile head bump

A 22-year-old man presented with a 5-year history of focal seizures and a pulsatile bump on the forehead (figure, A; video on the Neurology® Web site at Neurology.org). He had subtle right hemiparesis with facial palsy, Mini-Mental State Examination score of 22/30, and audible bruit on forehead swelling, suggesting cerebral proliferative angiopathy (CPA). This condition differs from arteriovenous malformation in in that hemorrhages are uncommon; it has a typically large size, with normal brain parenchyma between vascular spaces (figure, B).1 There are multiple arterial feeders (figure, C) with prominent draining veins (figure, D).1,2 Embolization or surgical resections are not usually possible with a CPA diagnosis.1

Source: Neurology - June 15, 2015 Category: Neurology Authors: Khwaja, G. A., Bohra, V., Duggal, A., Srivastava, A., Chaudhry, N. Tags: All Imaging, Other cerebrovascular disease/ Stroke, All Cognitive Disorders/Dementia, Arteriovenous malformation VIDEO NEUROIMAGES Source Type: research