The Effective Radiation Dose to Immune Cells Predicts Lymphopenia and Inferior Cancer Control in Locally Advanced NSCLC

CONCLUSIONS: EDIC is associated with inferior disease outcomes and the development of severe lymphopenia. Proton therapy is associated with lower EDIC. Further investigations to limit radiation dose to the immune system appear warranted.PMID:38008414 | DOI:10.1016/j.radonc.2023.110030

Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - November 26, 2023 Category: Radiology Authors: Cole Friedes Michelle Iocolano Sang Ho Lee Lian Duan Bolin Li Abigail Doucette Roger B Cohen Charu Aggarwal Lova L Sun William P Levin Keith A Cengel Gary Kao Boon-Keng Kevin Teo Corey J Langer Ying Xiao Jeffrey Bradley Steven J Feigenberg Nikhil Yegya-Ra Source Type: research