Comparative protective efficacy of a newly generated live recombinant thermostable highly attenuated vaccine rK148/GVII-F using a single regimen against lethal NDV GVII.1.1

Avian Pathol. 2023 Nov 27:1-19. doi: 10.1080/03079457.2023.2263395. Online ahead of print.ABSTRACTA thermostable, safe, and effective NDV GVII recombinant vaccine was generated.Fusion gene replacement with GVII did not affect GI K148/08 virus thermostability.Strain rK148/GVII-F provided adequate protection against a lethal NDV challenge.Oropharyngeal shedding was significantly reduced on post-challenge days 5 and 7.PMID:38009206 | DOI:10.1080/03079457.2023.2263395

Source: Avian Pathology - November 27, 2023 Category: Pathology Authors: Amal Abdallah Mouhamed Jiho Lee Deok-Hwan Kim Chang-Seon Song Source Type: research