Impact of Folinic Acid Dosing on Efficacy and Toxicity of High-Dose Methotrexate in Central Nervous System Lymphoma

CONCLUSION: Our findings suggest that optimizing FA dosing to avoid very high rescue doses may improve treatment outcomes in PCNSL patients receiving HDMTX. Further prospective studies are warranted to validate these findings.PMID:38008594 | DOI:10.1016/j.clml.2023.10.012

Source: Clinical Lymphoma and Myeloma - November 26, 2023 Category: Cancer & Oncology Authors: Arnon Haran Noa Gross Even-Zohar Michal Haran Eyal Lebel Shlomzion Aumann Adir Shaulov Moshe Gatt Boaz Nachmias Source Type: research